Z01

A translational and computational platform for longitudinal studies of SCLC under therapy

Z01 will provide platforms and technology to funnel clinical specimens that were collected longitudinally during the course of routine treatment of SCLC patients and as part of clinical trials. Z01 will therefore conduct a registry trial to collect clinical specimens, as well as all associated clinical data in a highly standardized fashion. Similarly, it will be critical to provide a computational platform to make this highly granular data available to all subprojects that seek to validate their findings in humans. Thus, Z01 will also provide database and –access technology that ensures searching the clinical and experimental data (e.g., from sequencing studies) in real time. Finally, Z01 will provide essential data analysis pipelines (e.g., for transcriptome sequencing) to the various subprojects that apply sequencing technology to mine their experimental samples. 

Principal Investigator

Univ. Prof. Dr. med. Jürgen Wolf SFB1399
Univ. Prof. Dr. med. Jürgen Wolf

Medical Director Center for Integrated Oncology CIO Köln

University Hospital of Cologne

Department I for Internal Medicine, Center for Integrated Oncology Köln Bonn (CIO)

Curriculum Vitae (CV)

Univ. Prof. Dr.-Ing. Ulrich Lang SFB1399
Univ. Prof. Dr.-Ing. Ulrich Lang

Professor (C4) and Director of the Regional Computing Center

University of Cologne

Institute for Computer Science and Regional Computing Centre (RRZK) Cologne

Curriculum Vitae (CV)

Univ. Prof. Dr. rer. nat. Martin Peifer SFB1399
Univ. Prof. Dr. rer. nat. Martin Peifer

Mildred-Scheel Professor on Computational Cancer Genomics (W2)

University of Cologne

Department of Translational Genomics and Center for Molecular Medicine (CMMC) 

Curriculum Vitae (CV)

Z01