In vivo imaging of tumors

This project aims to provide access to the imaging core facility, as well as support to all subprojects that need small animal imaging for their research. This central aspect will be of importance in all in vivo studies, where assessment of tumor growth and drug response is required. The main modality for longitudinal studies is MR Imaging, though other modalities such as SPECT, PET and CT can be used, as well. Secondary aims are the in vivo imaging of cancer associated fibroblasts using SPECT and PET to study their potential role in SCLC and the imaging of tumor development, using a reporter gene approach based on the sodium iodine symporter (mNIS) involving an SCLC mouse model expressing mNIS that allows visualization and quantification of tumor growth and metastases formation. 

Principal Investigator

Univ. Prof. Dr. rer. nat. Holger Grüll SFB1399
Univ. Prof. Dr. rer. nat. Holger Grüll

Professor (W2), Experimental Imaging and Image-guided Therapy

University Hospital of Cologne

Department of Radiology

Curriculum Vitae (CV)