C03

Immuno-peptidomics of SCLC

The peptides presented by MHC molecules on SCLC cells and their recognition by T cells have not been explored so far. H.-G. Rammensee and C. Gouttefangeas will decipher the MHC-class I and -class II ligandome of SCLC, identify immunogenic SCLC neo- and non-mutated T cell antigens, and characterize tumor-specific T cells in SCLC patients. In particular, personalized vaccination approaches based on patients´ tumor ligandome analysis should address the future design of SCLC immune therapies. 

Principal Investigator

Univ. Prof. Dr. rer. nat. Hans-Georg Rammensee SFB1399
Univ. Prof. Dr. rer. nat. Hans-Georg Rammensee

Professor (C4), Chair of the Department of Immunology

University of Tübingen

Institute of Cell Biology, Department of Immunology

Curriculum Vitae (CV)

PD Dr. rer. nat. Cécile Gouttefangeas SFB1399
PD Dr. rer. nat. Cécile Gouttefangeas

Group Leader

University of Tübingen

Interfaculty Institute for Cell Biology

Department of Immunology

Curriculum Vitae (CV)

C03