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Univ. Prof. Dr. med. Alexander Quaas

Academic education

1996 - 2002: Medical School, University of Hamburg

Scientific degrees

11/2014: Habilitation in Pathology, Faculty of Medicine, University of Hamburg     „Multiparametrische Prognosesysteme in humanen malignen Tumoren“
08/2006: M.D., Medical School, University of Hamburg, Magna cum Laude: “Aktivität und Expression von Telomerase in Neuroblastomen: eine molekularbiologische- und immunhistochemische Untersuchung” (Prof. Dr. med. Guido Sauter, Department of Pathology, University of Hamburg)
11/2002: Graduation from Medical School, University of Hamburg, Summa cum Laude

Scientific career

08/2015 - present: W2 full professorship, University of Cologne
05/2014 - present: Deputy-Director of the Institute of Pathology, University Hospital Cologne
06 - 12/2009: Postdoctoral research fellow, Department of Cellular Pathology, University of Birmingham (Group of Prof. Dr. Stefan Huebscher)

Contact Information

Univ. Prof. Dr. med. Alexander Quaas SFB1399
Univ. Prof. Dr. med. Alexander Quaas

Professor (W2) and Vice-Director of the Department of Pathology

University Hospital of Cologne

Institute of Pathology

Curriculum Vitae (CV)

10 most relevant publications

  • Trost F, Zhang B, Aring I, Bauer M, Glamann L, Wessolly M, Johnson K, Göbel H, Lerbs T, Sangenne T, Herrmann P, Mairinger F, Kopp C, Michels S, Rasokat A, Heldwein M, Wagner S, Schömig-Markiefka B, Wolf J, Hartmann S, Wickenhauser C, Bychkov A, Klussmann JP, Quaas A, Buettner R, Tolkach Y. An agentic framework for autonomous scientific discovery in cancer pathology. Nat Med. Published online April 29, 2026. doi:10.1038/s41591-026-04357-y
     
  • George J, Maas L, Abedpour N, Cartolano M, Kaiser L, Fischer RN, Scheel AH, Weber JP, Hellmich M, Bosco G, Volz.C, Mueller C, Dahmen I, John F, Alves CP, Werr L, Panse JP, Kirschner M, Engel-Riedel W, Jürgens J, Stoelben E, Brockmann M, Grau S, Sebastian M, Stratmann JA, Kern J, Hummel HD, Hegedüs B, Schuler M, Plönes T, Aigner C, Elter T, Toepelt K, Ko YD, Kurz S, Grohé C, Serke M, Höpker K, Hagmeyer L, Doerr F, Hekmath K, Strapatsas J, Kambartel KO, Chakupurakal G, Busch A, Bauernfeind FG, Griesinger F, Luers A, Dirks W, Wiewrodt R, Luecke A, Rodermann E, Diel A, Hagen V, Severin K, Ullrich RT, Reinhardt HC, Quaas A, Bogus M, Courts C, Nürnberg P, Becker K, Achter V, Büttner R, Wolf J, Peifer M, Thomas RK. Evolutionary trajectories of small cell lung cancer under therapy. Nature. 2024;627(8005):880-889. doi:10.1038/s41586-024-07177-7 
     
  • Tolkach Y, Wolgast LM, Damanakis A, Pryalukhin A, Schallenberg S, Hulla W, Eich ML, Schroeder W, Mukhopadhyay A, Fuchs M, Klein S, Bruns C, Büttner R, Gebauer F, Schömig-Markiefka B, Quaas A. Artificial intelligence for tumour tissue detection and histological regression grading in oesophageal adenocarcinomas: a retrospective algorithm development and validation study. Lancet Digit Health. 2023;5(5):e265-e275. doi:10.1016/S2589-7500(23)00027-4 
     
  • Klein S, Schulte A, Arolt C, Tolkach Y, Reinhardt HC, Buettner R, Quaas A. Intratumoral Abundance of M2-Macrophages is Associated with Unfavorable Prognosis and Markers of T-Cell Exhaustion in Small Cell Lung Cancer Patients. Modern Pathology. 2023;36(10):100272. doi:10.1016/j.modpat.2023.100272 
     
  • Quaas A, Biesma HD, Wagner AD, Verheij M, van Berge Henegouwen MI, Schoemig-Markiefka B, Pamuk A, Zander T, Siemanowski J, Sikorska K, Egthuijsen JMP, Meershoek-Klein Kranenbarg EM, van de Velde CJH, Buettner R, Alakus H, Cats A, Ylstra B, van Laarhoven HWM, van Grieken NCT. Microsatellite instability and sex differences in resectable gastric cancer – A pooled analysis of three European cohorts. Eur J Cancer. 2022;173:95-104. doi:10.1016/j.ejca.2022.06.025 
     

 

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