Univ. Prof. Dr. med. Alexander Quaas

Academic education

1996 - 2002: Medical School, University of Hamburg

Scientific degrees

11/2014: Habilitation in Pathology, Faculty of Medicine, University of Hamburg     „Multiparametrische Prognosesysteme in humanen malignen Tumoren“
08/2006: M.D., Medical School, University of Hamburg, Magna cum Laude: “Aktivität und Expression von Telomerase in Neuroblastomen: eine molekularbiologische- und immunhistochemische Untersuchung” (Prof. Dr. med. Guido Sauter, Department of Pathology, University of Hamburg)
11/2002: Graduation from Medical School, University of Hamburg, Summa cum Laude

Scientific career

08/2015 - present: W2 full professorship, University of Cologne
05/2014 - present: Deputy-Director of the Institute of Pathology, University Hospital Cologne
06 - 12/2009: Postdoctoral research fellow, Department of Cellular Pathology, University of Birmingham (Group of Prof. Dr. Stefan Huebscher)

10 most relevant publications

  • Pasternack H, Fassunke J, Plum PS, Chon SH, Hescheler DA, Gassa A, Merkelbach-Bruse S, Bruns CJ, Perner S, Hallek M, Büttner R, Bollschweiler E, Hölscher AH, Quaas A, Zander T, Weiss J, Alakus H. Somatic alterations in circulating cell-free DNA of oesophageal carcinoma patients during primary staging are indicative for post-surgical tumour recurrence. Sci Rep. 2018 Oct 8;8(1):14941
  • Hewitt LC, Inam IZ, Saito Y, Yoshikawa T, Quaas A, Hoelscher A, Bollschweiler E, Fazzi GE, Melotte V, Langley RE, Nankivell M, Cunningham D, Allum W, Hutchins GG, Grabsch HI. Epstein-Barr virus and mismatch repair deficiency status differ between oesophageal and gastric cancer: A large multi-center study. Eur J Cancer. 2018 May;94:104-114
  • Quaas A, Heydt C, Gebauer F, Alakus H, Loeser H, Buettner R, Hillmer A, Bruns C, Merkelbach-Bruse S, Zander T, Frommolt P. Genomic characterization of TP53-Wild-Type Esophageal Carcinoma. Transl Oncol. 2018 Oct 11;12(1):154-161
  • Grünewald I, Trautmann M, Busch A, Bauer L, Huss S, Schweinshaupt P, Vollbrecht C, Odenthal M, Quaas A, Büttner R, Meyer MF, Beutner D, Hüttenbrink KB, Wardelmann E, Stenner M, Hartmann W. MDM2 and CDK4 amplifications are rare events in salivary duct carcinomas. Oncotarget. 2016 Nov 15;7(46):75261-75272.
  • Helbig D, Ihle MA, Pütz K, Tantcheva-Poor I, Mauch C, Büttner R, Quaas A. Oncogene and therapeutic target analyses in atypical fibroxanthomas and pleomorphic dermal sarcomas. Oncotarget. 2016 Apr 19;7(16):21763-74.
  • Ozretić L, Wagner S, Huebbers CU, Gattenlöhner S, Klussmann JP, Beutner D, Zander T, Buettner R, Quaas A. FGFR1 amplification and co-overexpression of c-MYC in oropharyngeal squamous cell carcinoma. Oral Oncol. 2016 Mar;54:e7-9.
  • Quaas A, Rahvar AH, Burdelski C, Koop C, Eichelberg C, Rink M, Dahlem R, Schlomm T, Tsourlakis MC, Simon R, Minner S, Sauter G, Steurer S. βIII-tubulin overexpression is linked to aggressive tumor features and shortened survival in clear cell renal cell carcinoma. World J Urol. 2015 Oct;33(10):1561-9.
  • Quaas A, Oldopp T, Tharun L, Klingenfeld C, Krech T, Sauter G, Grob TJ. Frequency of TERT promoter mutations in primary tumors of the liver. Virchows Arch. 2014 Dec;465(6):673-7.
  • Katt J, Schwinge D, Schoknecht T, Quaas A, Sobottka I, Burandt E, Becker C, Neurath MF, Lohse AW, Herkel J, Schramm C. Increased T helper type 17 response to pathogen stimulation in patients with primary sclerosing cholangitis. Hepatology. 2013 Sep;58(3):1084-93.
  • Schrader J, Gordon-Walker TT, Aucott RL, van Deemter M, Quaas A, Walsh S, Benten D, Forbes SJ, Wells RG, Iredale JP. Matrix stiffness modulates proliferation, chemotherapeutic response, and dormancy in hepatocellular carcinoma cells. Hepatology. 2011 Apr;53(4):1192-205


Contact Information

Univ. Prof. Dr. med. Alexander Quaas SFB1399
Univ. Prof. Dr. med. Alexander Quaas

Professor (W2) and Vice-Director of the Department of Pathology

University Hospital of Cologne

Institute of Pathology

Curriculum Vitae (CV)