Dr. rer. nat. Laura Surace

Academic education

2006 – 2011 Bachelor and Master in Molecular Biology and Biochemistry, University of Pavia (grade= 110/110, cum laude)

Scientific degrees

09/2015 M. Phil. And Ph.D. in Immunology, University of Zürich, Switzerland; “Dissection of the mechanisms that support tumor-specific immunity upon radiotherapy” (Supervisor: Prof. Maries van den Broek)

09/2011 Diploma in Molecular Biology and Biochemistry, University of Pavia

Scientific career

since on 01/2023 Junior Group Leader, Max Eder Program, Deutsche Krebshilfe, University of Bonn, Institute of Clinical Chemistry and Clinical Pharmacology, Uniklinik Bonn, Germany

03/2022 – 12/202 Junior Group Leader, STEP program, University of Bonn, Institute of Clinical Chemistry and Clinical Pharmacology, Uniklinik Bonn, Germany

2021 – 2022 Postdoctoral research fellow, University of Bonn, Bonn, Germany (Group of Prof. Dr. Christoph Wilhelm)

2016 – 2021 Postdoctoral research fellow, Pasteur Institute, Paris, France (Group of Professor Dr. James Di Santo)

09/2015 – 01/2016 Intern at the Functional Genomic Center Zürich, Zürich, Switzerland (Group of Dr. Endre Lazko) – Mass spectrometry internship

Honors / Awards / Memberships

2022 Max Eder Grant for young group leader – Deutsche Krebshilfe

2022 Travel award – “ILC2022 – The 4th International Conference on Innate Lymphoid Cells” – Hawaii. Selected short talk

2022 Invited speaker – ENII summer school on advanced immunology – Sardinia, Italy

2022 STEP Program – for Young PI, University of Bonn

2018 – 2020 Marie Curie Postdoctoral Fellowship – Horizon Europe, European Research Executive Agency

Since 2018 Reviewer for Mucosal Immunology

2017 – 2020 Member, French Society of Immunology, Pasteur Institute, France

2017 Member of the Scientific and Organization Committees of the “Microbes, Immunity and Metabolism International Conference” at Institute Pasteur

2016 – 2018 Early Postdoc Fellowship – Swiss National Science Foundation, Switzerland

2017 Short talk and travel awards – 7th International Conference on Complement Therapeutics – Greece.

2016 Nomination for Mercator Award – Graduate Campus Zurich, Switzerland

2015 Award for Outstanding Doctoral Thesis – University of Zurich, Switzerland

2013 Poster prize – 5th Cancer Network Retreat – Grindelwald

2012 Prize for best poster – “Outstanding poster award” – ENII Spring School on Advanced Immunology – Ralph Steinman Memorial

2009 EDISU special award for Master Thesis – University of Pavia, Italy

2007 – 2011 EDISU university scholarship – University of Pavia, Italy

Contact Information

Dr. rer. nat. Laura Surace SFB1399
Dr. rer. nat. Laura Surace

Junior Group Leader (STEP program - University of Bonn)

University of Bonn/Uniklinik Bonn

Institute of Clinical Chemistry and Clinical Pharmacology

Curriculum Vitae (CV)

10 most relevant publications

  • Karagiannis, F.*, Peukert, K.*, Surace, L.*, Michla, M., Fox, M., Weiss, P., Feuerborn, C., Schulz, S., Burcu, A., Seeliger, B., Welte, T., David, S., Grondman, I., H de Nooijer, A., Pickkers, P., Berger, M.M., Brenner, T., Putensen, C., Garbi, N., Netea, M.G., Placek, K., Bode, C. and Wilhelm, C. The Ketone body β-hydroxybutyratemetabolicallyrestores T cell function in severe COVID-19. Nature, 2022 Jul 28. Doi: 10.1038/s41586-022-05128-8. * Authors equally contributed to the work. Co-authorship.
  • Croft CA, Thaller A, Marie S, Doisne JM, Surace L, Yang R, Puel A, Bustamante J, Casanova JL, Di Santo JP. Notch, RORC and IL-23 signals cooperate to promote multi-lineage human innate lymphoid cell differentiation. Nat Commun. 2022 Jul 27;13(1):4344. Doi: 10.1038/s41467-022-32089-3. PMID: 35896601; PMCID: PMC9329340.
  • Surace L, Wilhelm C. Keeping ILCs in shape: PD-1 as a metabolic checkpoint. Nat Metab. 2022 Jul;4(7):794-795. Doi: 10.1038/s42255-022-00599-5. PMID: 35788759.
  • Surace L, Di Santo JP. Local and systemic features of ILC immunometabolism. Curr Opin Hematol. 2022 Jul 1;29(4):209-217. Doi: 10.1097/MOH.0000000000000722. PMID: 35787549.
  • Serafini, N., Jarade, A., Surace, L., Goncalves, P., Sismeiro, O., Varet, H., Legendre, R., Coppee, J.Y., Durum, S.K., Frankel, G. and Di Santo, J.P. (2022). Trained ILC3 responses promote intestinal defense. Science, 375(6583):859-863.
  • Surace, L., Doisne, J. M., Escoll, P., Marie, S., Dardalhon, V., Croft, C., Thaller, A., Topazio, D., Sparaneo, A., Cama, A., Musumeci, O., d’Ecclesia, A., Buchrieser, C., Taylor, N., & Di Santo, J. P. (2021). Polarized mitochondria as guardians of NK cell fitness. Blood advances, 5(1), 26–38.
  • Surace L, Doisne JM, Croft CA, Thaller A, Escoll P, Marie S, Petrosemoli N, Guillemot V, Dardalhon V, Topazio D, Cama A, Buchrieser C, Taylor N, Amit I, Musumeci O, Di Santo JP. Dichotomous metabolic networks govern human ILC2 proliferation and function. Nat Immunol. 2021 Nov;22(11):1367-1374. Doi: 10.1038/s41590-021-01043-8. Epub 2021 Oct 22. PMID: 34686862; PMCID: PMC8553616.
  • Lim, A. I., Li, Y., Lopez-Lastra, S., Stadhouders, R., Paul, F., Casrouge, A., Serafini, N., Puel, A., Bustamante, J., Surace, L., Masse-Ranson, G., David, E., Strick-Marchand, H., Le Bourhis, L., Cocchi, R., Topazio, D., Graziano, P., Muscarella, L. A., Rogge, L., Norel, X., Sallenave, J.M., Allez, M., Graf, T., Hendriks, R.W., Casanova, J.L., Amit, I., Yssel, H., Di Santo, J. P. (2017). Systemic Human ILC Precursors Provide a Substrate for Tissue ILC Differentiation. Cell, 168(6), 1086–1100.e10
  • Surace, L., Lysenko, V., Fontana, A. O., Cecconi, V., Janssen, H., Bicvic, A., Okoniewski, M., Pruschy, M., Dummer, R., Neefjes, J., Knuth, A., Gupta, A., & van den Broek, M. (2015). Complement is a central mediator of radiotherapy-induced tumor-specific immunity and clinical response. Immunity, 42(4), 767–777.
  • Martínez-Barricarte R, Markle JG, Ma CS, Deenick EK, Ramírez-Alejo N, Mele F, Latorre D, Mahdaviani SA, Aytekin C, Mansouri D, Bryant VL, Jabot-Hanin F, Deswarte C, Nieto-Patlán A, Surace L, Kerner G, Itan Y, Jovic S, Avery DT, Wong N, Rao G, Patin E, Okada S, Bigio B, Boisson B, Rapaport F, Seeleuthner Y, Schmidt M, Ikinciogullari A, Dogu F, Tanir G, Tabarsi P, Bloursaz MR, Joseph JK, Heer A, Kong XF, Migaud M, Lazarov T, Geissmann F, Fleckenstein B, Arlehamn CL, Sette A, Puel A, Emile JF, van de Vosse E, Quintana-Murci L, Di Santo JP, Abel L, Boisson-Dupuis S, Bustamante J, Tangye SG, Sallusto F, Casanova JL. Human IFN-γ immunity to mycobacteria is governed by both IL-12 and IL-23. Sci Immunol. 2018 Dec 21;3(30):eaau6759. Doi: 10.1126/sciimmunol.aau6759. PMID: 30578351; PMCID: PMC6380365.