CV
Dr. rer. nat. Laura Kolb
Academic education
2012 – 2016 Doctorate in Biotechnology and Bioengineering, “Stem cell niche engineering through photopatterning and microfluidics” (supervisor: Prof. Matthias Lutolf), Laboratory of Stem Cell Bioengineering, EPF Lausanne (EPFL), Switzerland
2005 – 2012 Diploma studies in biology, University of Freiburg, Germany, Diploma Thesis “Humanized stimulus-responsive biohybrid materials for biomedical application” (supervisor Prof. Wilfried Weber), Laboratory of Synthetic Biology, University of Freiburg, Germany
Scientific degrees
2016 PhD in Biotechnology and Bioengineering, EPF Lausanne (EPFL), Switzerland, supervisor Matthias Lutolf
2012 Diploma Biology, University of Freiburg, supervisor Prof. Wilfried Weber
Scientific career
2019 – present Head of „Clinical Cancer Genomics“, TRON gGmbH at the University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany
2017 – 2019 Scientist „Clinical Cancer Genomics“, TRO N gGmbH at the University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany
2016 – 2017 Postdoctoral research fellow, Laboratory of Stem Cell Bioengineering (Prof. Matthias Lutolf), EPFL, Switzerland
Honors / Awards / Memberships
2018 – present Member Association for Cancer Immunotherapy CIMT e.V.
Contact Information
Dr. rer. nat. Laura Kolb
Head of Clinical Cancer Genomics within the Biomarker
Johannes Gutenberg University Mainz gGmbH
TRON - Translational Oncology
10 most relevant publications
- Beck JD, Diken M, Suchan M, Streuber M, Diken E, Kolb L, Allnoch L, Vascotto F, Peters D, Beißert T, Akilli-Öztürk Ö, Türeci Ö, Kreiter S, Vormehr M, Sahin U. Long-lasting mRNA-encoded interleukin-2 restores CD8+ T cell neoantigen immunity in MHC class I-deficient cancers. Cancer Cell. 2024;42(4):568-582.e11. doi:10.1016/j.ccell.2024.02.013
- Krienke C, Kolb L, Diken E, Streuber M, Kirchhoff S, Bukur T, Akilli-Öztürk Ö, Kranz LM, Berger H, Petschenka J, Diken M, Kreiter S, Yogev N, Waisman A, Karikó K, Türeci Ö, Sahin U. A noninflammatory mRNA vaccine for treatment of experimental autoimmune encephalomyelitis. Science (1979). 2021;371(6525):145-153. doi:10.1126/science.aay3638
- Kolb L, Allazetta S, Karlsson M, Girgin M, Weber W, Lutolf MP. High-throughput stem cell-based phenotypic screening through microniches. Biomater Sci. 2019;7(8):3471-3479. doi:10.1039/C8BM01180J
- Kobel SA, Kolb L, Lutolf MP. 2.9 Materials as Artificial Stem Cell Microenvironments. Comprehensive Biomaterials II. Elsevier; 2017:179-201. doi:10.1016/B978-0-12-803581-8.10150-X
- Allazetta S, Kolb L, Zerbib S, Bardy J, Lutolf MP. Cell-Instructive Microgels with Tailor-Made Physicochemical Properties. Small. 2015;11(42):5647-5656. doi:10.1002/smll.201501001
- Mosiewicz KA*, Kolb L*, van der Vlies AJ*, Lutolf MP. Microscale patterning of hydrogel stiffness through light-triggered uncaging of thiols. Biomater Sci. 2014;2(11):1640-1651. doi:10.1039/C4BM00262H *equal contributions
- Mosiewicz KA*, Kolb L*, van der Vlies AJ, Martino MM, Lienemann PS, Hubbell JA, Ehrbar M, Lutolf MP. In situ cell manipulation through enzymatic hydrogel photopatterning. Nat Mater. 2013;12(11):1072-1078. doi:10.1038/nmat3766 *equal contributions
- Geraths C, Eichstädter L, Gübeli RJ, Christen EH, Friedrich C, Weber W. Synthesis and characterization of a stimulus-responsive l-ornithine-degrading hydrogel. Journal of Controlled Release. 2013;165(1):38-43. doi:10.1016/j.jconrel.2012.10.022
