CV
Dr. nat. med. Maria Cartolano
Academic education
2003 – 2007: DPhil studies in Life Sciences, Max Planck Institute for Plant breeding Research, Cologne, Germany.
1997 – 2002: MSc in Plant Biotechnology at the University of Naples “Federico II”.
Scientific career
2015 – present: Post-doctoral fellow at University Hospital of Cologne
2013 – 2015: Post-doctoral fellow at Max Planck Institute for Plant Breeding Research of Cologne
2009 – 2013: Post-doctoral fellow at University of Oxford (Department of Plant Sciences)
Honors / Awards / Memberships
2009 – 2011: Post-doctoral Research Fellowship funded by the Federation of European Biochemical Societies (FEBS): “The genetic architecture of the Cardamine hirsuta diversity in leaf shape.”
Contact Information
Dr. nat. med. Maria Cartolano
Junior research group leader
University of Cologne
Department of Translational Genomics
10 most relevant publications
- Gräf CM, Reese M, Vicente-Luque A, Mönig N, Bruzeau C, Nadeu F, Latacz M, Bihler J, Meinel J, Cartolano M, Peifer M, Beà S, Campo E, Thelen M, Bröckelmann PJ, Jachimowicz RD. Establishment and characterization of a CCND1-rearranged non-mantle cell lymphoma cell line and patient-derived xenograft model. Leukemia. 2026;40(3):666-670. doi:10.1038/s41375-025-02849-3
- Langpape A, Bonasera D, Stroh J, Reese M, Cartolano M, Liccardi G, von Karstedt S. Redox destabilization by ibrutinib promotes ferroptosis in diffuse large B-cell lymphoma (DLBCL). Cell Death Discov. 2025;11(1):495. doi:10.1038/s41420-025-02826-w
- Werr L, Bartenhagen C, Rosswog C, Cartolano M, Voegele C, Sexton-Oates A, di Genova A, Ernst A, Kahlert Y, Hemstedt N, Höppner S, Mansuet Lupo A, Pelosi G, Brcic L, Papotti M, George J, Bosco G, Quaas A, Tang LH, Robzyk K, Kadota K, Roh MS, Fanaroff RE, Falcon CJ, Büttner R, Lantuejoul S, Rekhtman N, Rudin CM, Travis WD, Alcala N, Fernandez-Cuesta L, Foll M, Peifer M, Thomas RK, Fischer M. TERT Expression and Clinical Outcome in Pulmonary Carcinoids. Journal of Clinical Oncology. 2025;43(2):214-225. doi:10.1200/JCO.23.02708
- Ibruli O, Rose F, Beleggia F, Schmitt A, Cartolano M, Torres Fernández LA, Saggau J, Bonasera D, Kiljan M, Gozum G, Lichius L, Cai J, Niu L na, Caiaffa MI, Herter JM, Walczak H, Liccardi G, Grüll H, Büttner R, Bosco G, George J, Thomas RK, Bozek K, Reinhardt HC, Herter-Sprie GS. A novel mouse model recapitulating the MMR-defective SCLC subtype uncovers an actionable sensitivity to immune checkpoint blockade. J Cancer Res Clin Oncol. 2024;150(11):496. doi:10.1007/s00432-024-05942-9
- George J, Maas L, Abedpour N, Cartolano M, Kaiser L, Fischer RN, Scheel AH, Weber JP, Hellmich M, Bosco G, Volz C, Mueller C, Dahmen I, John F, Alves CP, Werr L, Panse JP, Kirschner M, Engel-Riedel W, Jürgens J, Stoelben E, Brockmann M, Grau S, Sebastian M, Stratmann JA, Kern J, Hummel HD, Hegedüs B, Schuler M, Plönes T, Aigner C, Elter T, Toepelt K, Ko YD, Kurz S, Grohé C, Serke M, Höpker K, Hagmeyer L, Doerr F, Hekmath K, Strapatsas J, Kambartel KO, Chakupurakal G, Busch A, Bauernfeind FG, Griesinger F, Luers A, Dirks W, Wiewrodt R, Luecke A, Rodermann E, Diel A, Hagen V, Severin K, Ullrich RT, Reinhardt HC, Quaas A, Bogus M, Courts C, Nürnberg P, Becker K, Achter V, Büttner R, Wolf J, Peifer M, Thomas RK. Evolutionary trajectories of small cell lung cancer under therapy. Nature. 2024;627(8005):880-889. doi:10.1038/s41586-024-07177-7
- Rosswog C, Fassunke J, Ernst A, Schömig-Markiefka B, Merkelbach-Bruse S, Bartenhagen C, Cartolano M, Ackermann S, Theissen J, Blattner-Johnson M, Jones B, Schramm K, Altmüller J, Nürnberg P, Ortmann M, Berthold F, Peifer M, Büttner R, Westermann F, Schulte JH, Simon T, Hero B, Fischer M. Genomic ALK alterations in primary and relapsed neuroblastoma. Br J Cancer. 2023;128(8):1559-1571. doi:10.1038/s41416-023-02208-y
- Müller N, Lorenz C, Ostendorp J, Heisel FS, Friese UP, Cartolano M, Plenker D, Tumbrink H, Heimsoeth A, Baedeker P, Weiss J, Ortiz-Cuaran S, Büttner R, Peifer M, Thomas RK, Sos ML, Berg J, Brägelmann J. Characterizing Evolutionary Dynamics Reveals Strategies to Exhaust the Spectrum of Subclonal Resistance in EGFR-Mutant Lung Cancer. Cancer Res. 2023;83(15):2471-2479. doi:10.1158/0008-5472.CAN-22-2605
- Rosswog C, Bartenhagen C, Welte A, Kahlert Y, Hemstedt N, Lorenz W, Cartolano M, Ackermann S, Perner S, Vogel W, Altmüller J, Nürnberg P, Hertwig F, Göhring G, Lilienweiss E, Stütz AM, Korbel JO, Thomas RK, Peifer M, Fischer M. Chromothripsis followed by circular recombination drives oncogene amplification in human cancer. Nat Genet. 2021;53(12):1673-1685. doi:10.1038/s41588-021-00951-7
- Cartolano M*, Abedpour N*, Achter V, Yang TP, Ackermann S, Fischer M, Peifer M. CaMuS: simultaneous fitting and de novo imputation of cancer mutational signature. Sci Rep. 2020;10(1):19316. doi:10.1038/s41598-020-75753-8 *equal contributions
- Ackermann S*, Cartolano M*, Hero B, Welte A, Kahlert Y, Roderwieser A, Bartenhagen C, Walter E, Gecht J, Kerschke L, Volland R, Menon R, Heuckmann JM, Gartlgruber M, Hartlieb S, Henrich KO, Okonechnikov K, Altmüller J, Nürnberg P, Lefever S, de Wilde B, Sand F, Ikram F, Rosswog C, Fischer J, Theissen J, Hertwig F, Singhi AD, Simon T, Vogel W, Perner S, Krug B, Schmidt M, Rahmann S, Achter V, Lang U, Vokuhl C, Ortmann M, Büttner R, Eggert A, Speleman F, O’Sullivan RJ, Thomas RK, Berthold F, Vandesompele J, Schramm A, Westermann F, Schulte JH, Peifer M, Fischer M. A mechanistic classification of clinical phenotypes in neuroblastoma. Science (1979). 2018;362(6419):1165-1170. doi:10.1126/science.aat6768 * equal contributions
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